Fluorosilicone oil is a polysiloxane with fluoroalkyl side chain. Fluorosilicone oil combines the advantages of silicone and organofluorine polymers, with low surface energy and excellent solvent resistance, oil resistance, weather resistance wear resistance, high and low temperature resistance, oxidation resistance and weather resistance, etc. It has become the best among lubricants. The grease prepared with fluorosilicone oil can be used for lubrication and sealing of vacuum equipment, lubrication of rolling bearings of conveyor belt, permanent lubrication of bearings of low-temperature equipment, and lubrication and sealing of parts in contact with benzene solvent, lubricating oil contact hose, gaskets, seals, fuel tank lining, etc. Fluorosilicone oil grease is usually made of fluorosilicone oil as raw material, adding solid lubricant or compound solid lubricant and suitable additives. Commonly used solid lubricants are: PTFE micronized powder, molybdenum disulfide, graphite, tungsten disulfide, etc. Among them, PTFE micronized powder has both lubricating and thickening effects, and is compatible with fluorosilicone oil, which is irreplaceable by other solid lubricants. With the increase of dupont ptfe powder, the sintering load of fluorosilicone oil grease is greatly improved, but the anti-wear and friction reduction performance is not well improved; PTFE micronized powder has better oil absorption ability. The dropping point is above -200℃. Nanoscale and micron PTFE powder as grease thickener have thickening properties, the difference between the two is as follows: 1, Grease to the same micro cone into the degree, the amount of nanoscale PTFE micro powder than micron PTFE micro powder less. 2, With the increase in the amount of nano-level PFE micronized powder, the friction coefficient of grease and abrasion marks change very little; and with the increase in the amount of micronized PTFE micronized powder, the friction coefficient of grease and abrasion marks change more, indicating that the thickener particles coarse but play the role of abrasive wear. 3, Nanometer PTFE powder and micron PTFE powder can improve the sintering load of grease, but not the more the better; when the amount of PTFE powder added to a certain extent, the sintering load of grease change is not obvious. 4, The best mass fraction of nanoscale PTFE is 26%, the best mass fraction of micron PTFE is 32%. In addition, fluorosilicone grease in the application of the actual situation and requirements, the reasonable addition of other solid lubricants, such as aluminum disulfide, para-polyphenylene, tungsten disulfide and graphite, etc., to improve its friction reduction and anti-wear performance.